The film is set in a fantasy world around Winston, a typical weakling who works as a cleaner at a fitness club. Doctors diagnose him with a terminal illness that requires expensive treatment, but his greedy employer refuses to pay. Tired of waiting, Winston decides to take matters into his own hands and rob the company. However, during the attempt, he falls into a toxic waste pit that changes him forever. He transforms into a new kind of hero: the Toxic Avenger. Now, Toxie must become a savior and confront the ruthless corporate overlords and corrupt forces that threaten his son, friends, and community. In a world where greed reigns... justice is best served radioactively.